Rumex dentatus синтез наночастиц серебра, антимикробная активность и характеристика

AgNPs (Silver Nanoparticles) are frequently used in medicine due to their potent antimicrobial activity and AgNPs effectively produced by a variety of physico-chemical and photochemical reduction. Polygonaceae family comprises 200 species; Rumax dentatus are one of them present worldwide, used as food, exhibiting flavors, taste, and aroma and mild laxative properties, and utilized as medicine for a long time. In our current study, the chemical synthesis of silver nanoparticles (AgNPs) using the extract of plant species Rumax dentatus was reported. Extraction was performed through the soxhlet method. Additionally, the nanoparticles were screened against gram-positive Staphylococcus aureus and gram-negative Escherichia coli bacterial strains. The chemical-synthesized NPs (Nanoparticles) were characterized using UV–Visible spectroscopy, XRD (X‑ray diffraction) and SEM (scanning electron microscopy) for structural morphology average size and confirmation of AgNPs. The shift of yellow to brown-red color indicated by the extract showed the chemical synthesis of AgNPs. The greater antimicrobial activity was found against Escherichia coli and closed to standard control. XRD and SEM morphological analysis showed morphological characteristics showed agglomerated polydispersed spherical shape of nanoparticles as and indicated high displayed inconsistent morphology which caused by aggregation or agglomeration of nanoparticles and is accountable of Rumax dentatus plant extractAgNPs (наночастицы серебра) часто используются в медицине из-за их мощной антимикробной активности, а AgNPs эффективно образуются в результате различных физико-химических и фотохимических восстановлений. Семейство Polygonaceae насчитывает 200 видов; Rumax dentatus – один из них, присутствующий во всем мире, используемый в пищу, обладающий вкусом и ароматизатором и мягкими слабительными свойствами, а также долгое время применяемый в качестве лекарства. В нашем текущем исследовании сообщалось о химическом синтезе наночастиц серебра (AgNPs) с использованием экстракта вида растений Rumax dentatus. Экстракцию проводили по методу Сокслета. Кроме того, наночастицы были подвергнуты скринингу на грамположительный золотистый стафилококк и грамотрицательные штаммы бактерий Escherichia coli. Химически синтезированные NPS (наночастицы) были охарактеризованы с использованием УФ‑видимой спектроскопии, XRD (дифракция рентгеновских лучей) и SEM (сканирующая электронная микроскопия) для определения структурной морфологии, среднего размера и подтверждения AgNPs. Изменение желтого цвета на коричнево-красный, отмеченное экстрактом, свидетельствовало о химическом синтезе AgNPs. Более высокая антимикробная активность была обнаружена в отношении Escherichia coli и не поддавалась стандартному контролю. Рентгеновский и СЭМ‑морфологический анализы показали, что морфологические характеристики показали агломерированную полидисперсную сферическую форму наночастиц as и указали на высокую степень непоследовательности морфологии, которая вызвана агрегацией или агломерацией наночастиц и обусловлена растительным экстрактом Rumax dentatu

Antibacterial, Antifungal, Cytotoxic, Phytotoxic, Insecticidal, and Enzyme Inhibitory Activities of Geranium wallichianum

The present study describes the phytochemical investigations of the crude extracts of rhizomes and leaves of Geranium wallichianum. The crude extracts were fractionated to obtain n-hexane, ethyl acetate, and n-butanol fractions, which were subjected to different biological activities and enzyme inhibition assays to explore the therapeutic potential of this medicinally important herb. The results indicated that the crude extracts and different fractions of rhizomes and leaves showed varied degree of antimicrobial activities and enzyme inhibitions in different assays. Overall, the rhizome extract and its different fractions showed comparatively better activities in various assays. Furthermore, the purified constituents from the repeated chromatographic separations were also subjected to enzyme inhibition studies against three different enzymes. The results of these studies showed that lipoxygenase enzyme was significantly inhibited as compared to urease. In case of chemical constituents, the sterols (2–4) showed no inhibition, while ursolic acid (1) and benzoic ester (6) showed significant inhibition of urease enzymes

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements